Brochure of the Sirius 2 LB 9526 Tube Luminometer
PDF | 495.9 KB
Download nowThe Sirius 2 detects less than 0.5 zmol of firefly luciferase (1 amol ATP/tube). Light collection is maximized through the close proximity of the sample to the detector and the use of optimized light reflectors surrounding the sample vial. The detector is operated in photon counting mode, which ensures a very low background signal for excellent signal to noise ratio and the highest linearity.
The sample chamber is designed for performance and flexibility: just pick the sample format that fits your application best. The optional sample holders enable accurate injection into both, microcentrifuge tubes and standard luminescence tubes.
The system is compatible with a variety of sample formats:
The touchscreen-driven software is very intuitive and operated by touch gestures. The easy-to-use software provides advanced features, such as handling of replicates, dual assay calculations, and display of graphics.
Data can be downloaded easily onto a USB stick or printed. The results can be exported for further calculation in Excel or other programs.
Closing of the sample drawer automatically initiates the measurement. There´s no need to press any key. The automatic light shutter protects the detector from ambient light. This makes the system ready for measurement from the moment the door is closed. This means that there is no need to set a long delay before the measurement. This is necessary with most other tube luminometers so that the background can return to the initial level after the door has been opened.
The system is available with up to two syringe-type automatic reagent injectors. The injection volume range is 20–500 μL. This very broad volume range allows the Sirius 2 to adapt to any assay using injectors. Ready-to go sample holders for precise injection are available for 1.5 ml and 2 ml microfuge tubes, as well as for 55 mm and 75 mm, 12 mm diameter tubes (standard format for most luminescence assays).
Detectors | Low-noise photomultiplier tube in single photon counting mode |
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Detection technologies | Luminescence |
Measurement modes | Endpoint, Kinetics, Multiple Kinetics |
Spectral range luminescence | 300-600 nm |
Injectors | Up to 2 syringe injectors |
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Injector volume | 20-500 µL |
Tube formats | Luminescence tubes, 12 x 55 mm Luminescence tubes, 12 x 75 mm Microcentrifuge tubes, 1.5 and 2 mL |
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Luminescence sensitivity | <1 amol ATP/tube (ATP HS assay) |
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Dynamic range | 6 orders of magnitude |
Interface |
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Display (integrated computer) | 7” capacitive touch, gesture control, 480 x 800 pixels |
External interfaces (integrated computer) | 2x USB 2.0, 1x Ethernet (RJ-45) |
Printer interface (integrated computer) | Network or USB printing (PCL6 or Postscript 3) |
Data export | CSV (Excel), PDF, HTML formats |
Available protocols |
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Power Supply | 110-240 V, 24 V/2.5 A DC |
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Temperature tolerance | Storage: 0-40° C Operation: 15-35° C |
Humidity tolerance | Storage: up to 80% non-condensing Operation: up to 70% non-condensing |
Dimensions (W x D x H) | 349 x 150 x 241 mm |
Weight | 3.6 kg |
Brochure of the Sirius 2 LB 9526 Tube Luminometer
PDF | 495.9 KB
Download nowABEL® Cell Activation Assay for Whole Blood or Isolated Cells with Pholasin® and…
EN | PDF | 175.4 KB
Download nowBelow amol ATP detection limit with Sirius L Tube Luminometer and ATP Reagent SS…
PDF | 234.9 KB
Download nowRapid Bacterial Detection Assay (Useful Biology) with the Sirius L Tube…
EN | PDF | 499.3 KB
Download nowKinetic Luminescent bacteria test for Measuring the Toxicity of Solid and…
PDF | 568.1 KB
Download nowEN | PDF | 2.1 MB
Download nowEN | PDF | 789.5 KB
Download nowv2.0.0.32. For FB12 tube luminometer and all Sirius models.
EN | ZIP | 17.3 MB
Download nowBrochure of the Sirius 2 LB 9526 Tube Luminometer
PDF | 495.9 KB
Download nowABEL® Cell Activation Assay for Whole Blood or Isolated Cells with Pholasin® and…
EN | PDF | 175.4 KB
Download nowBelow amol ATP detection limit with Sirius L Tube Luminometer and ATP Reagent SS…
PDF | 234.9 KB
Download nowRapid Bacterial Detection Assay (Useful Biology) with the Sirius L Tube…
EN | PDF | 499.3 KB
Download nowKinetic Luminescent bacteria test for Measuring the Toxicity of Solid and…
PDF | 568.1 KB
Download nowEN | PDF | 2.1 MB
Download nowEN | PDF | 789.5 KB
Download nowv2.0.0.32. For FB12 tube luminometer and all Sirius models.
EN | ZIP | 17.3 MB
Download nowThe Sirius 2 is a very recent instrument and thus not many papers using it have yet been published. Here you have a selection of articles which feature the Sirius 2 or the Sirius L, which are very similar.
Year | Authors | Journal | Title | Method |
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2024 | Vladimir Sokolov, Olga Kyrchanova, Natalia Klimenko, Anna Fedotova, Airat Ibragimov, Oksana Maksimenko, Pavel Georgiev | Nucleic Acids Research | Dual luciferase | |
2022 | Xia Guo, Christudas Sunil, Oluwaseun Adeyanju, Andrew Parker, Steven Huang, Mitsuo Ikebe, Torry A. Tucker, Steven Idell, and Guoqing Qian | Scientific Reports | Firefly luciferase reporter | |
2021 | Luigi D’Angelo, Elisa Astro, Monica De Luise, Ivana Kurelac, Nikkitha Umesh-Ganesh, Shujing Ding, Ian M. Fearnley, Giuseppe Gasparre, Massimo Zeviani, Anna Maria Porcelli, Erika Fernandez-Vizarra, and Luisa Iommarini | Cell Reports | ATP synthesis rate assay | |
2021 | Simona Plesselova, Pablo Garcia-Cerezo, Victor Blanco, Francisco J. Reche-Perez, Fernando Hernandez-Mateo, Francisco Santoyo-Gonzalez, María Dolores Giron-Gonzalez, and Rafael Salto-Gonzalez | Journal of Medicinal Chemistry | ATP assay | |
2020 | Fahimeh Ghavamipour, Hossein Rahmani, Maryam Shanehsaz, Khosro Khajeh, Manouchehr Mirshahi, and Reza H. Sajedi | Journal of Nanobiotechnology | Chemiluminescent ELISA | |
2019 | Yuwan Zhao, Xin Zeng, Huancheng Tang, Dongcai Ye and Jianjun Liu | Oncology Letters | Caspase-Glo® 3/7, ATP Assay | |
2019 | Mingning Qiu, Sai Zhang, Longzhi Ke, Huancheng Tang, Xin Zeng, and Jianjun Liu | Oncology Letters | ATP Assay, Caspase-Glo® 3/7, Caspase-Glo® 9 | |
2018 | Gabriela Jírová, Alena Vlková, Martina Wittlerová, Markéta Dvořáková, Lucie Kašparová, Jan Chrz, Kristina Kejlová, Zdeňka Wittlingerová, Magdaléna Zimová, Barbora Hošíková, Jana Jiravová, Hana Kolářová | Neuroendocrinology Letters | Toxicity of wastewater from health care facilities assessed by different bioassays | Water toxicity with Vibrio fischeri |
2017 | Zinaida M. Kaskova, Felipe A. Dörr, Valentin N. Petushkov, Konstantin V. Purtov, Aleksandra S. Tsarkova, Natalja S. Rodionova, Konstantin S. Mineev, Elena B. Guglya, Alexey Kotlobay, Nadezhda S. Baleeva, Mikhail S. Baranov, Alexander S. Arseniev, Josef I. Gitelson, Sergey Lukyanov, Yoshiki Suzuki, Shusei Kanie, Ernani Pinto, Paolo Di Mascio, Hans E. Waldenmaier, Tatiana A. Pereira, Rodrigo P. Carvalho, Anderson G. Oliveira, Yuichi Oba, Erick L. Bastos, Cassius V. Stevani, and Ilia V. Yampolsky | Science Advances | Fungal luciferase | |
2017 | Ignacio A. Rodriguez-Brenes, Andrew Hofacre, Hung Fan and Dominik Wodarz | PLoS Computational Biology | Dual luciferase | |
2015 | Mingning Qiu, Lieqian Chen, Guobin Tan, Longzhi Ke, Sai Zhang, Hege Chen and Jianjun Liub | Scientific Reports | Caspase-Glo® 3/7, ATP Assay | |
2015 | Juan‐Ping Yu, Xi‐Guang Xu, Rui‐Juan Ma, Shi‐Ni Qin, Cong‐Rong Wang, Xiao‐Bo Wang, Ming Li, Ming‐Song Li, Qiang Ma, and Wei‐Wen Xu | Journal of Clinical Laboratory Analysis | Acridinium ester |
You can find additional publications which have used older Sirius instruments in publication databases.
Please keep in mind that the list provided is not exhaustive, but it offers valuable examples of experiments performed with our instruments and published in peer-reviewed journals.